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About Sioux Falls

Sioux Falls has worked hard to build a reputation as a great place to work, shop, live or raise a family. And now, it’s an emerging leader in healthcare and medical research. 



City Size

Centrally located on the northern plains, Sioux Falls is a regional hub for healthcare, retail, finance and business services. The city is South Dakota’s largest and one of America’s crossroad cities at the junction of Interstates 90 and 29.
  • Population of Sioux Falls: 141,000
  • Population of Sioux Falls and surrounding metro area: 211,000
  • Sioux Falls land size: 61.5 square miles




Great for Businesses and Families.

Companies flourish in Sioux Falls, as the city consistently ranks near the top of national studies on quality of life, low crime, low tax burden, low unemployment and business prosperity.
  • #1 Corporate Business Climate— Pollina Corporate Real Estate
  • #1 Lowest Cost of Doing Business – Milken Institute
  • #1 Small Place for Business and Careers – Forbes
  • #1 in Small Business Survival Index – Small Business & Entrepreneurship Council
  • #2 Lowest Cost Bio Med Location in North America – Boyd Companies
  • #45 of Top 100 Best Places to Live and Launch a Business – CNNMoney
  • South Dakota is ranks 2nd in technology in education
  • South Dakota is ranks 7th in inbound population migration
Area residents enjoy and support a wide range of cultural activities, and the city has a lower cost of living than Minneapolis, MN; Denver, CO; Lincoln, NE; and Missoula, MT.


Sanford's Economic Impact

  • 7.8% of the total labor force in the Sioux Falls metropolitan area is employed by Sanford Health.
  • 10% of the total personal income in the Sioux Falls area is generated by Sanford Health.
  • Sanford Health has an annual payroll over $322.2 million in the Sioux Falls metro area.
  • Sanford Health invests approximately $30 million per year in capital expenditures in the Sioux Falls metropolitan area.